J Med Assoc Thai 1998; 81 (2):103

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Maternal and Neonatal Effects of Single-Dose Epidural Anesthesia with Lidocaine and Morphine for Cesarean Delivery
Niruthisard S Mail, Somboonviboon W , Thaithumyanon P , Mahutchawaroj N , Chaiyakul A

Two per cent lidocaine (18-20 ml) with epinephrine 1:200,000 plus 4 mg of morphine was
given as a single epidural injection over 3 minutes for elective cesarean section in 60 healthy
mothers at term. It provided effective, safe and adequate analgesia in the postoperative period.
There was no evidence of neonatal depression related to the epidural morphine as judged by Apgar
scores at I and 5 minutes and umbilical venous pH at birth. Maternal and umbilical venous
levels of morphine were measured and found to be low at birth. However, this study was done
only in healthy mothers not in labor and having a term fetus. We do not recommend using this
technique in complicated obstetric patients.

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