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Original ArticleOpen Access
Short Term Effects of Atenolol in Patients with Dilated Cardiomyopathy
Krittayaphong R 
,
Mahanonda N ,
Kangkagate C ,
Phankingthongkum R ,
Chaithiraphan S
,
Mahanonda N ,
Kangkagate C ,
Phankingthongkum R ,
Chaithiraphan S Dilated cardiomyopathy is a common cause of heart failure with systolic dysfunction.
Medications used to treat this condition are usually for symptomatic relief. We studied the effect
of atenolol in heart failure caused by dilated cardiomyopathy in a double blinded randomized
fashion. There were 17 males and 5 females. All patients underwent right and left heart catheterization,
coronary angiography, endomyocardial biopsy, exercise testing and doppler echocardiography.
By 3 months, atenolol significantly reduced resting and exercise heart rate and
pulmonary capillary wedge pressure. There was no difference in exercise capacity. We conclude
from this study that atenolol improve hemodynamic condition in patients with dilated cardiomyopathy
without improving exercise capacity during this short observertion period.
Medications used to treat this condition are usually for symptomatic relief. We studied the effect
of atenolol in heart failure caused by dilated cardiomyopathy in a double blinded randomized
fashion. There were 17 males and 5 females. All patients underwent right and left heart catheterization,
coronary angiography, endomyocardial biopsy, exercise testing and doppler echocardiography.
By 3 months, atenolol significantly reduced resting and exercise heart rate and
pulmonary capillary wedge pressure. There was no difference in exercise capacity. We conclude
from this study that atenolol improve hemodynamic condition in patients with dilated cardiomyopathy
without improving exercise capacity during this short observertion period.
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