J Med Assoc Thai 1998; 81 (4):283

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Comparison of Ketoprofen and Morphine for Post-operative Analgesia in Orthopaedic Patients
Vathana P Mail, Pakpianpairoj C , Prasartritha T

A prospective, open label, randomized study to compare efficacy of intramuscular
administration of ketoprofen and morphine for post operative analgesia in elective orthopaedic
surgery was performed in 50 patients. The procedures were open reduction and internal
fixation of long bone fractures (26 cases), hip replacement (9 cases) and spinal surgery ( 15
cases). Pain intensity and pain relief in both groups were evaluated at 1, 3 and 6 hours postinjection.
There was no significant differences in pain relief of both groups (P=0.05). The side
effects of intramuscular ketoprofen were encountered in only 8 per cent.
Ketoprofen injection is an alternative for post operative pain relief.

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