J Med Assoc Thai 1998; 81 (5):365

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Harlequin Baby : A Case Report
Singalavanija S Mail, Sangtawesin V , Horpoapan S , Ratrisawadi V

Harlequin fetus is a rare and the most severe form of congenital ichthyosis. Most of the
infants die within a few weeks after birth due to sepsis and respiratory difficulties. The case of
a female harlequin baby is reported. The baby survived because of good neonatal intensive
care, topical emollients and oral etretinate. Now she is over three years old and the skin developed
into congenital non-bullous ichthyosiform erythroderma. Unfortunately she had delayed
growth and development. This is the first case report of a harlequin fetus in Thailand that had
prolonged survival.

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