J Med Assoc Thai 1998; 81 (6):397

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Postmenopausal Osteoporosis : What is the Real Magnitude of.,Hle Problem in the Thai Population?
Taechakraichana N Mail, Angkawanich P , Panyakhamlerd K , Limpaphayom K

To assess the prevalence of osteoporosis, bone mass measurement was performed on
1 ,04 7 women attending a menopause clinic at Chulalongkorn Hospital, Bangkok. The mean age
of the population was 50.5±5.7 years. The bone density was measured at lumbar spines (LS)
(Ll-L4) and the non-dominant femoral neck (FN) site utilizing a Hologic QDR 2000 dual energy
X-ray absorptiometer. According to the World Health Organization's (WHO) definition a value of
bone mineral density (BMD) that is more than 2.5 standard deviation (SD) below the young
adult mean is considered diagnostic of osteoporosis. In this study, Thai and American cut-off
values of BMD for osteoporosis were used to compare the prevalence of osteoporosis. Using Thai's
cutoff value, the results showed a lower prevalence of osteoporosis of both LS and FN (15.7%
and 9.5%, respectively). Considering the subgroups of the studied population, the prevalence of
osteoporosis of LS and FN utilizing Thai's cutoff value was significantly higher in postmenopausal
than in premenopausal women. (Premenopause vs postmenopause, LS : 4. 7% vs 21.4%;
FN : 4.7% vs 11.9%, respectively, P

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