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Original ArticleOpen Access
Thyroid Scintigraphy in Children with Hypothyroidism: A Five-year Experience
Pusuwan P 
,
Likitmaskul S ,
Wacharasindhu S ,
lntarasupht S ,
Mungkharak J ,
Chiewvit S ,
Pleehachinda R
,
Likitmaskul S ,
Wacharasindhu S ,
lntarasupht S ,
Mungkharak J ,
Chiewvit S ,
Pleehachinda R The presence or absence of thyroid glandular tissue demonstrated by thyroid scintigraphy
is important for genetic and prognostic counseling and for acceleration of diagnosis in other
affected siblings. Technetium-99m-pertechnetate thyroid scintigraphy was performed on 27
children with cretinism at the Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital
during the 5-year period from June 1991. Based on scintigraphic findings, three main groups
of thyroid localization were seen. Thirteen ( 48.1%) were athyrotic while 3 (11.1%) had an ectopic
thyroid and 11 (40.8%) had gland in normal position. Perchlorate discharge test was performed
in 8 children of the last group and the results were positive indicating an organification defect.
Thyroid scintigraphy and perchlorate discharge test provided the useful information for
diagnosis, follow-up, and prognosis in children with cretinism.
is important for genetic and prognostic counseling and for acceleration of diagnosis in other
affected siblings. Technetium-99m-pertechnetate thyroid scintigraphy was performed on 27
children with cretinism at the Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital
during the 5-year period from June 1991. Based on scintigraphic findings, three main groups
of thyroid localization were seen. Thirteen ( 48.1%) were athyrotic while 3 (11.1%) had an ectopic
thyroid and 11 (40.8%) had gland in normal position. Perchlorate discharge test was performed
in 8 children of the last group and the results were positive indicating an organification defect.
Thyroid scintigraphy and perchlorate discharge test provided the useful information for
diagnosis, follow-up, and prognosis in children with cretinism.
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