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Original ArticleOpen Access
Effect of Umbilical Vein Oxytocin Injection on the Third Stage of Labor : A Randomized Controlled Study
Kovavisarach E 
,
Rojsangruang S
,
Rojsangruang S To evaluate the effect of umbilical vein oxytocin injection on the duration of third stage
of labor, and estimated blood loss within 24 hours postpartum, in 50 vaginal parturients at
Rajavithi Hospital from March 1, 1994 and June 30, 1995. The parturients were randomized to
administered either an umbilical vein injection of 20 units of oxytocin diluted to 20 ml with
normal saline (oxytocin group) or only normal saline 20 ml (control group) immediately after
cord clamping. There were 25 paturients in each group. The duration of the third stage of labor
in the oxytocin group was significantly shorter than that in the control group. In only I case of
the control group was manual placental removal performed. The estimated blood loss within
24 hours postpartum in both groups was not statistically different. Twenty units of umbilical
vein oxytocin injection was effective to shorten the duration of the third stage of labor but
were not effective to reduce the estimated blood loss within 24 hours postpartum. The need for
a further large scale study in the future was suggested.
of labor, and estimated blood loss within 24 hours postpartum, in 50 vaginal parturients at
Rajavithi Hospital from March 1, 1994 and June 30, 1995. The parturients were randomized to
administered either an umbilical vein injection of 20 units of oxytocin diluted to 20 ml with
normal saline (oxytocin group) or only normal saline 20 ml (control group) immediately after
cord clamping. There were 25 paturients in each group. The duration of the third stage of labor
in the oxytocin group was significantly shorter than that in the control group. In only I case of
the control group was manual placental removal performed. The estimated blood loss within
24 hours postpartum in both groups was not statistically different. Twenty units of umbilical
vein oxytocin injection was effective to shorten the duration of the third stage of labor but
were not effective to reduce the estimated blood loss within 24 hours postpartum. The need for
a further large scale study in the future was suggested.
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