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Case ReportOpen Access
Epithelial-Myoepithelial Carcinoma of Parotid Gland : A Case Report with Immunohistochemical and Ultrastructural Studies
Shuangshoti S 
,
Lutigaviboon V ,
Kasantikul V
,
Lutigaviboon V ,
Kasantikul V A 66-year-old man presented with a painless mass of the parotid gland. Light and electron
microscopic studies verified the basic nature of the tumor as epithelial-myoepithelial carcinoma,
a low-grade malignant neoplasm of the salivary gland. Pathologically, there were two types of
cells; the inner eosinophilic epithelial cells lining the ducts and the outer clear cells. The
former cells displayed immunoreactivity for cytokeratin and ultrastructural features of apical
microvilli and desmosome. The latter cells were positive for actin, S-1 00 protein, vimentin
and the cytoplasm contained actin microfilaments. Such pathological findings were characteristic
features of this rare tumor. To our knowledge, this is the first reported case of EMC in Thailand.
microscopic studies verified the basic nature of the tumor as epithelial-myoepithelial carcinoma,
a low-grade malignant neoplasm of the salivary gland. Pathologically, there were two types of
cells; the inner eosinophilic epithelial cells lining the ducts and the outer clear cells. The
former cells displayed immunoreactivity for cytokeratin and ultrastructural features of apical
microvilli and desmosome. The latter cells were positive for actin, S-1 00 protein, vimentin
and the cytoplasm contained actin microfilaments. Such pathological findings were characteristic
features of this rare tumor. To our knowledge, this is the first reported case of EMC in Thailand.
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