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Original ArticleOpen Access
The Diagnostic Value of Anorectal Manometry as a Screening Test for Hirschsprung's Disease
Osatakul S 
,
Patrapinyokul S ,
Osatakul N
,
Patrapinyokul S ,
Osatakul N The diagnostic accuracy of anorectal manometry as a screening test for Hirschsprung's
disease (HD) was assessed in 46 children suspected of having HD on clinical grounds. Among 33
children in whom a rectosphincteric reflex (RSR) was not demonstrated on manometric
recordings, 31 were later proven to have HD by full thickness rectal biopsy : the remaining 2 children
were shown not to have HD. None of the 12 children who had a normal RSR had HD. Thus, two
false positive diagnoses were observed in this study, giving an overall diagnostic accuracy by
anorectal manometry of 95 per cent and diagnostic sensitivity of 100 per cent. Anorectal manometry
is an accurate, non-invasive test which has a place as the screening test of choice for HD.
Key word : Anorectal Manometry, Diagnosis, Hirschsprung's Disease
disease (HD) was assessed in 46 children suspected of having HD on clinical grounds. Among 33
children in whom a rectosphincteric reflex (RSR) was not demonstrated on manometric
recordings, 31 were later proven to have HD by full thickness rectal biopsy : the remaining 2 children
were shown not to have HD. None of the 12 children who had a normal RSR had HD. Thus, two
false positive diagnoses were observed in this study, giving an overall diagnostic accuracy by
anorectal manometry of 95 per cent and diagnostic sensitivity of 100 per cent. Anorectal manometry
is an accurate, non-invasive test which has a place as the screening test of choice for HD.
Key word : Anorectal Manometry, Diagnosis, Hirschsprung's Disease
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