J Med Assoc Thai 1999; 82 (11):1136

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Reference Value for Urinary Deoxypyridinoline as a Specific Marker for Measuring Bone Resorption in Thais
Pidetcha P Mail, lntramanee S , Patrakarn K , Leelahakul P

In the next century, the increasing number of elderly and nsing healthcare costs will
bring with it metabolic bone problems, particularly osteoporosis. Deoxypyridinoline: Dpd in urine
is a sensitive and specific marker for screening and monitoring of bone resorption in a variety
of diseases affecting bone turnover and in risk groups especially in the postmenopause. The
reference value among aging (21-60 years) of a healthy well defined group was studied by collecting
the urine between 700-1000 hours and using the ELISA technique to determine the level
of Dpd. The reference value of Dpd in 113 males and 298 females 1.3-6.5 and 1.5-6.9 nm Dpd/nm
Creatinine respectively. The level of Dpd in females was significantly higher than in males at

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