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Original ArticleOpen Access
Reference Value for Urinary Deoxypyridinoline as a Specific Marker for Measuring Bone Resorption in Thais
In the next century, the increasing number of elderly and nsing healthcare costs will
bring with it metabolic bone problems, particularly osteoporosis. Deoxypyridinoline: Dpd in urine
is a sensitive and specific marker for screening and monitoring of bone resorption in a variety
of diseases affecting bone turnover and in risk groups especially in the postmenopause. The
reference value among aging (21-60 years) of a healthy well defined group was studied by collecting
the urine between 700-1000 hours and using the ELISA technique to determine the level
of Dpd. The reference value of Dpd in 113 males and 298 females 1.3-6.5 and 1.5-6.9 nm Dpd/nm
Creatinine respectively. The level of Dpd in females was significantly higher than in males at
p
bring with it metabolic bone problems, particularly osteoporosis. Deoxypyridinoline: Dpd in urine
is a sensitive and specific marker for screening and monitoring of bone resorption in a variety
of diseases affecting bone turnover and in risk groups especially in the postmenopause. The
reference value among aging (21-60 years) of a healthy well defined group was studied by collecting
the urine between 700-1000 hours and using the ELISA technique to determine the level
of Dpd. The reference value of Dpd in 113 males and 298 females 1.3-6.5 and 1.5-6.9 nm Dpd/nm
Creatinine respectively. The level of Dpd in females was significantly higher than in males at
p
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