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Original ArticleOpen Access
Fine Needle Aspiration Cytology of Thymoma
Tangthangtlzam A 
,
Chonmaitri ! ,
Subhannachart P ,
Tungsagunwattwza S
,
Chonmaitri ! ,
Subhannachart P ,
Tungsagunwattwza S Thymoma is the 2nd most common mediastinal tumor found in Thai people. Cytologically
it has a characteristic biphasic cell pattern and can be differentiated from other mediastinal
lesions. We reviewed 14 aspirated samples, initially diagnosed as thymoma among a total
of 80 mediastinal aspirations, obtained during a period of 6 years. Revised cytologic diagnosis
was made and compared with histopathology from needle biopsy, surgical biopsy and surgical
removal in each case. All cytologic samples revealed a mixture of epithelial cells and lymphocytes
in varying proportions. Histopathologic samples were available in 13 patients and
showed 12 thymomas and 1 immature teratoma. While all thymomas revealed characteristic
cytologic features, a case of mediastinal immature teratoma with unsatisfactory aspirated
sample revealed resembling features and it was very difficult to differentiate such a tumor from
thymoma.
Key word : Aspiration Cytology, Thymoma
it has a characteristic biphasic cell pattern and can be differentiated from other mediastinal
lesions. We reviewed 14 aspirated samples, initially diagnosed as thymoma among a total
of 80 mediastinal aspirations, obtained during a period of 6 years. Revised cytologic diagnosis
was made and compared with histopathology from needle biopsy, surgical biopsy and surgical
removal in each case. All cytologic samples revealed a mixture of epithelial cells and lymphocytes
in varying proportions. Histopathologic samples were available in 13 patients and
showed 12 thymomas and 1 immature teratoma. While all thymomas revealed characteristic
cytologic features, a case of mediastinal immature teratoma with unsatisfactory aspirated
sample revealed resembling features and it was very difficult to differentiate such a tumor from
thymoma.
Key word : Aspiration Cytology, Thymoma
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