Views: 1,265 | Downloads:
18
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Hormonal Ablation Therapy for Metastatic Prostatic Carcinoma : A Review
Leewansangtong S 
,
Soontrapa S
,
Soontrapa S Hormonal therapy is the standard treatment for metastatic prostatic carcinoma. The conventional
surgical or medical androgen ablation therapy seems to have a similar response. Despite
a higher response of CAB compared to conventional castration in metastatic disease, the controversy
of survival benefit remains unsolved. Immediate treatment should be given in metastatic
disease particularly in patients who have minimal metastases. In patients who have progression
after CAB, antiandrogens should be withdrawn. The choices of optimal therapies for prostate
cancer depend not only on the survival but also the quality of life and cost effect. Thus, the critical
factors for approaching prostate cancer are appropriate patient selection and stratification. Implicit
with this approach should maximize benefit from maximal androgen ablation therapy for patients
who are likely to profit from it. Finally, the development of experiments, clinical trials, and novel
therapeutic strategies may provide better management for prostate cancer in the future.
Key word : Metastatic Prostatic Carcinoma, Hormonal Ablation Therapy, Review
surgical or medical androgen ablation therapy seems to have a similar response. Despite
a higher response of CAB compared to conventional castration in metastatic disease, the controversy
of survival benefit remains unsolved. Immediate treatment should be given in metastatic
disease particularly in patients who have minimal metastases. In patients who have progression
after CAB, antiandrogens should be withdrawn. The choices of optimal therapies for prostate
cancer depend not only on the survival but also the quality of life and cost effect. Thus, the critical
factors for approaching prostate cancer are appropriate patient selection and stratification. Implicit
with this approach should maximize benefit from maximal androgen ablation therapy for patients
who are likely to profit from it. Finally, the development of experiments, clinical trials, and novel
therapeutic strategies may provide better management for prostate cancer in the future.
Key word : Metastatic Prostatic Carcinoma, Hormonal Ablation Therapy, Review
Download:
PDF