J Med Assoc Thai 1999; 82 (4):374

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Comparative Studies on Iodine Levels in Gallstones and Bile of Japanese and Thais (Chiang Mai and Bangkok)
Naito E Mail, Pausawasdi A , Miki M , Tanaka M

We measured the iodine content of gallstones and bile from patients in three areas
(Kawasaki in Japan, and Chiang Mai and Bangkok in Thailand) by means of neutron activation
analysis. The mean values for iodine content in three types of gallstones (cholesterol, pigment and
rare stones) and bile from patients living in Chiang Mai were clearly smaller than those from
patients living in Kawasaki and Bangkok. The low iodine intake by Chiang Mai patients continued
from the start of gallstone formation until the time when the stones were excised, and the iodine
intake was low when bile was collected. The PBI levels in the sera of Chiang Mai residents with
low iodine intake over a long period were clearly lower than those of Bangkok patients with normal
intake, and the levels in goiter patients were similar to those in healthy people and patients with
gallstones among Chiang Mai residents.
Key word : Gall Stone, Bile, Iodine Level, Japanese, Thai

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