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Case ReportOpen Access
Embryonic Testicular Regression Syndrome : A Case Report
A case of testicular regression syndrome was reported. The patient was an 18 year old
girl presenting with primary amenorrhoea. Physical examination revealed normal female external
genitalia and underdeveloped secondary sexual characteristics. Hormonal profile indicated gonadal
failure. Chromosome analysis revealed 46,XY karyotype. Diagnostic laparoscopy demomstrated
undeveloped internal genital organs. Remnants of epididymis, vas deferens and seminiferous tubule
were uncovered during exploratory laparotomy. Ontogeny of sexual differentiation and pathogenesis
of testicular regression syndrome were reviewed and discussed.
Key word : Hermaphrodite, Testicular Regression
girl presenting with primary amenorrhoea. Physical examination revealed normal female external
genitalia and underdeveloped secondary sexual characteristics. Hormonal profile indicated gonadal
failure. Chromosome analysis revealed 46,XY karyotype. Diagnostic laparoscopy demomstrated
undeveloped internal genital organs. Remnants of epididymis, vas deferens and seminiferous tubule
were uncovered during exploratory laparotomy. Ontogeny of sexual differentiation and pathogenesis
of testicular regression syndrome were reviewed and discussed.
Key word : Hermaphrodite, Testicular Regression
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