J Med Assoc Thai 1999; 82 (6):552

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Survival Analysis of Thai Patients with Non-Small-Cell Lung Cancer Undergoing Surgical Resection
Riantawan P Mail, Koanantakoo T , Chotivatanapong T , Wongsangiem M

This study examined the survival duration among patients with non-small-cell lung cancer
(NSCLC) undergoing surgical resection from January 1988 to December 1992 at the Central Chest
Hospital, Thailand. Patients were followed-up until death or survival as of September 1997. Survival
durations for different stages were analysed by Kaplan-Meier analysis and log rank test.
A total of 127 patients with histologically proved NSCLC underwent 79 lobectomies,
9 bilobectomies, 39 pneumonectomies during 1988-1992. The mean age was 60 years (SD 10.4).
There were 103 males and 24 females. Percentage of histologic types were: 59 per cent adenoCA,
35 per cent squamous cell CA, and 6 per cent large celiCA. Survival analysis was feasible in 88
patients, 38 alive and 50 deaths. 1-yr, 2-yr, and 5-yr survival were as following : 85 per cent, 78
per cent, and 60 per cent in stage 1 (n = 47); 70 per cent, 50 per cent, and 30 per cent in stage 2 (n =
12); and 54 per cent, 23 per cent, and 15 per cent in stage 3a (n = 29) [log rank 19.06, df 2, p =
0.0001]. Based on the present study, the survival outcome in patients with lung cancer beyond stage
I is uniformly poor. Measures should be made to diagnose early stage disease and expedite
surgery in order that a better survival outcome can be achieved.
Key word : Lung Cancer, Surgery, Survival

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