J Med Assoc Thai 1999; 82 (7):721

Views: 1,564 | Downloads: 25 | Responses: 0

PDF XML Respond to this article Print Alert & updates Request permissions Email to a friend


A Post Marketing Survey on the Side-effects of Loxoprofen
Waikakul S Mail, Waikakul W

A survey study of the efficacy and side-effects of loxoprofen in orthopaedic outpatient
clinics was carried out from January 1995 to December 1997. There were 1206 patients (569 males
and 637 females) with an average age of 56.4 ± 14.9 years. The youngest was 43 and the oldest
was 79 years. About 36 per cent of the patients had underlying diseases and 31 per cent were
receiving other medications as well as loxoprofen.
About 91 per cent of the patients were satisfied with loxoprofen in terms of pain control
and decreased inflammation. However, 8.4 per cent had side-effects, the most common being GI and
CNS disturbances. Some patients (0.24%) had GI bleeding and needed hospitalization. The high
risk patients were female older than 60 years who had used loxoprofen continuously for more
than 6 weeks. However, we conclude that loxoprofen is an effective NSAID with few side-effects.
Key word : NSAIDS, Post-marketing Survey, Loxoprofen

Download: PDF