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Original ArticleOpen Access
Efficacy of Laparoscopic Ovulation Induction in Polycystic Ovary Syndrome
Weerakiet S 
,
Srisombut C ,
Choktanasiri W ,
Rojanasakul A
,
Srisombut C ,
Choktanasiri W ,
Rojanasakul A This prospective study was aimed to evaluate the efficacy of laparoscopic ovarian
electrocoagulation in women with PCOS. Twenty-three PCOS women who had refractory to
clomiphene citrate attending the Reproductive Endocrinology Unit, Ramathibodi Hospital between
March 1995 and June 1998 were enrolled in the study. In all patients, electrocoagulation on the
ovarian surface of both ovaries was performed through laparoscope under general anesthesia.
Two patients were lost to follow-up for unknown reasons. The remaining 21 women had a mean
age of 30.3 ± 3.9 years (range 21-39) and mean duration of infertility of 4.1 ± 2.8 years (range 1-11 ).
There was no intra-operative and post-operative complication. After surgery, ovulation was
documented in 16 out of 18 (88.9%) patients. Fifteen (71.4%) patients became pregnant. Fourteen
pregnancies (93.3%) occurred within 9 months after surgery. Twelve women (80%) became pregnant
in spontaneous cycles without any treatment. The outcomes of pregnancies were 10 live
births, 3 ongoing pregnancies and 2 abortions. This study reveals the high efficacy of ovarian
electrocoagulation in infertile women with PCOS. High pregnancy and low abortion rates are
convincing. This surgical technique should be the treatment of choice for women with CC-resistant
PCOS.
Key word : Polycystic Ovary Syndrome,
electrocoagulation in women with PCOS. Twenty-three PCOS women who had refractory to
clomiphene citrate attending the Reproductive Endocrinology Unit, Ramathibodi Hospital between
March 1995 and June 1998 were enrolled in the study. In all patients, electrocoagulation on the
ovarian surface of both ovaries was performed through laparoscope under general anesthesia.
Two patients were lost to follow-up for unknown reasons. The remaining 21 women had a mean
age of 30.3 ± 3.9 years (range 21-39) and mean duration of infertility of 4.1 ± 2.8 years (range 1-11 ).
There was no intra-operative and post-operative complication. After surgery, ovulation was
documented in 16 out of 18 (88.9%) patients. Fifteen (71.4%) patients became pregnant. Fourteen
pregnancies (93.3%) occurred within 9 months after surgery. Twelve women (80%) became pregnant
in spontaneous cycles without any treatment. The outcomes of pregnancies were 10 live
births, 3 ongoing pregnancies and 2 abortions. This study reveals the high efficacy of ovarian
electrocoagulation in infertile women with PCOS. High pregnancy and low abortion rates are
convincing. This surgical technique should be the treatment of choice for women with CC-resistant
PCOS.
Key word : Polycystic Ovary Syndrome,
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