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Case ReportOpen Access
Severe Catatonia and Neuroleptic Malignant Syndrome: Report of 3 Cases
Kasantikul D 
,
Kanchananakhin P
,
Kanchananakhin P Catatonia is a syndrome characterized by motor rigidity or stupor, negativism, mutism and
inappropriate or bizarre posture. Without proper management, patients may have significant
morbidity and mortality from stupor, coma and death (lethal or malignant catatonia).
Neuroleptic malignant syndrome (NMS) is characterized by a sudden appearance of
motor rigidity, fever, autonomic effect, increased white blood cell count, serum creatinine phosphokinase,
liver enzymes, and myoglobin. The mortality rate is 15 per cent to 25 per cent or even
higher when depot form of neuroleptic is used. We report a patient with severe catatonia and
two cases of NMS. Death was encountered with one of the latter.
Key word : Catatonia, Neuroleptic Malignant Syndrome
inappropriate or bizarre posture. Without proper management, patients may have significant
morbidity and mortality from stupor, coma and death (lethal or malignant catatonia).
Neuroleptic malignant syndrome (NMS) is characterized by a sudden appearance of
motor rigidity, fever, autonomic effect, increased white blood cell count, serum creatinine phosphokinase,
liver enzymes, and myoglobin. The mortality rate is 15 per cent to 25 per cent or even
higher when depot form of neuroleptic is used. We report a patient with severe catatonia and
two cases of NMS. Death was encountered with one of the latter.
Key word : Catatonia, Neuroleptic Malignant Syndrome
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