J Med Assoc Thai 1999; 82 (11):129

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Plasma Free Amino Acid Contents in Healthy Thai Subjects
Sirichakwal P Mail, Feungpean B , Tontisirin K

This preliminary investigation determined the plasma amino acid concentrations in 136
healthy subjects. The subjects were divided into four groups according to their ages: gr I; 1-3
years, gr 2; 4-11 years, gr 3; 12-19 years and gr 4; 20-45 years.
Comparing among the groups, the results showed that in younger children (age 1-3
years) the essential amino acids were slightly lower than the other groups. A wide range for
most amino acids were observed. The ratio of essential (EAA): non-essential amino acid (NEAA)
in very young children ( 1-3 years) was lower than children, adolescents and adults. These ratios
were normal (> 0.5).
The data have been compared with those from several studies performed in normal
healthy subjects of different age groups, races and dietary habits. The results showed that most
of the mean values of individual amino acid were higher than others except cystine. The EAA:
NEAA ratio of each age group was comparable with other reports. The mean values of plasma
amino acids and EAA:NEAA ratio in healthy subjects were determined for diagnosis, follow-up
and prognosis of malnourished condition, abnormal amino acid metabolism and as a reference for
other purposes.
Key word : Plasma Amino Acids, Healthy Thai

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