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Original ArticleOpen Access
Pulmonary Involvement in Childhood Systemic Lupus Erythematosus
Chantarojanasiri T 
,
Sittirath A ,
Preutthipan A ,
Tapaneya0arn W ,
Suwanjutha S
,
Sittirath A ,
Preutthipan A ,
Tapaneya0arn W ,
Suwanjutha S Twenty-four children (aged 6-15 years, M : F = 1 : 11) with systemic lupus erythematosus
(SLE), who had respiratory symptoms, were retrospectively reviewed. Chest
radiographs obtained from all patients revealed pleural effusion in 13, a! veolar infiltration in 9.
pericardia! effusion and cardiomegaly in 6, interstitial infiltration in 4, hilar adenopathy in 3, lung
abscess in 2 and pneumatocele with pneumothorax in 1. Etiologic organisms were identified in
7 cases; (3 cases of nocardia isolated from pleural effusion and sputum, 2 cases of tuberculosis.
I case with staphylococcus aureus septicemia and 1 case with salmonella septicemia). All except
one patient improved with medical treatment. One patient died from pneumonitis. Although
pulmonary involvement is increasingly recognized in children with SLE, neither roentgenogram
nor clinical findings were specific. The differentiation of pulmonary infiltrates caused by lupus
lung disease from pulmonary infection should be carefully evaluated.
Key word : Pulmonary Disease, SLE
(SLE), who had respiratory symptoms, were retrospectively reviewed. Chest
radiographs obtained from all patients revealed pleural effusion in 13, a! veolar infiltration in 9.
pericardia! effusion and cardiomegaly in 6, interstitial infiltration in 4, hilar adenopathy in 3, lung
abscess in 2 and pneumatocele with pneumothorax in 1. Etiologic organisms were identified in
7 cases; (3 cases of nocardia isolated from pleural effusion and sputum, 2 cases of tuberculosis.
I case with staphylococcus aureus septicemia and 1 case with salmonella septicemia). All except
one patient improved with medical treatment. One patient died from pneumonitis. Although
pulmonary involvement is increasingly recognized in children with SLE, neither roentgenogram
nor clinical findings were specific. The differentiation of pulmonary infiltrates caused by lupus
lung disease from pulmonary infection should be carefully evaluated.
Key word : Pulmonary Disease, SLE
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