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Original ArticleOpen Access
A Comparison of Four Primary Classes of Antihypertensive Monotherapy in Thai Patients
Sukonthasam A 
Efficacy of four primary classes of antihypertensive agents (diuretics, angiotensin con-
verting enzyme inhibitors, calcium antagonists, adrenergic inhibiting drugs) were compared by
using a crossectional medical record survey between July 1997 and January 1998. Only
hypertensive cases with initial monotherapy were studied. The evaluations were
I)
blood pressure response after drug titration and 2) blood pressure response during the mainte-
nance phase. Two hundred and eighty nine patients were studied. After dose titration, the mean
reduction in systolic blood pressure with calcium antagonists (33เธ‘24 mmHg, mean เธ‘ SD) was
better than other drugs (p
verting enzyme inhibitors, calcium antagonists, adrenergic inhibiting drugs) were compared by
using a crossectional medical record survey between July 1997 and January 1998. Only
hypertensive cases with initial monotherapy were studied. The evaluations were
I)
blood pressure response after drug titration and 2) blood pressure response during the mainte-
nance phase. Two hundred and eighty nine patients were studied. After dose titration, the mean
reduction in systolic blood pressure with calcium antagonists (33เธ‘24 mmHg, mean เธ‘ SD) was
better than other drugs (p
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