J Med Assoc Thai 2000; 83 (11):1415

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Preschool Sarcoidosis
Wisuthsarewong W Mail, Viravan S , Manonukul J

Sarcoidosis is a multisystemic granulomatous disorder of unknown etiology, most com-
monly affecting young adults and presenting most frequently with bilateral hilar lymphadeno-
pathy, pulmonary infiltration, and skin or eye lesions. Sarcoidosis in children under the age of 4,
preschool sarcoidosis, is rare and has very different clinical mainfestations characterized by the
typical triad of skin, eye and joint involvement without lung disease. Diagnosis is established when
compatible clinical findings are supported by histological evidence of widespread noncaseating
epithelioid-cell granulomas in more than one organ or a positive Kveim-Siltzbach skin test. This
report describes a 2-year-old Thai girl with typical clinical manifestations of preschool sarcoidosis.
The histopathological studies of tissue specimens and the laboratory investigations support the
diagnosis of sarcoidosis. The patient responded to systemic corticosteroid therapy.
Key word : Preschool Sarcoidosis, Sarcoidosis

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