J Med Assoc Thai 2000; 83 (4):398

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Lipiodol Enhanced CT Scanning of Malignant Hepatic Tumors
Eurvilaichit C Mail

From August 1984 to March 1991, 41 patients with malignant liver tumors, 30 males
and 11 females, aged 30-75 years were treated at Ramathibodi Hospital with injection of
mitomycin-C lipiodol emulsion into the tumor
via
the feeding artery followed by embolization
of the feeding artery with gelfoam particles.
The patients comprised 30 cases of hepatocellular carcinoma, 4 cases of cholangio-
carcinoma and 7 cases of metastatic tumors of which one was from CA stomach, three were
from CA breast, and three from CA colon. The vascularity of the tumor was assessed in
angiogram obtained prior to treatment and retention pattern of lipiodol in the tumor was
evaluated in lipiodol-enhanced CT scan images taken 2-4 weeks following therapy.
The results showed that lipiodol CT scan images exhibited four patterns of lipiodol
retention in the tumor appearing as opacity as follows (l) homogenous (2) heterogeneous
(3) ring -like and (4) none. Lipiodol retention pattern appeared to be somewhat related to
vascularity of the tumor. Most of the hypervascular tumors such as hepatocellular carcinoma had
homogeneous lipiodol accumulation pattern if the tumor size was less than 5 em. Metastatic
tumors and cholangiocarcinoma showed heterogeneous or ring -like pattern of lipiodol accu-
mulation because they were relatively hypovascular. Hypervascular hepatocellular carcinoma may
exhibit heterogeneous or ring -like pattern if they are larger than 5 ems, and have multiple
feeding arteries, necrosis or A V shunting. Hepatocellular carcinoma with A V shunting may not
show any lipiodol accumulation at all.
Key word : Lipiodol CT Scan, Malignant Hepatic Tumors

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