Views: 1,296 | Downloads:
29
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Maintenance ECT in Treatment-Resistant Schizophrenia
Chanpattana W 
Although electroconvulsive therapy (ECT) has been used to treat schizophrenia since its
inception in 1938, its efficacy as long-term treatment is still controversial. A 2-Phase, prospective
study has been conducted in 21 patients with schizophrenia. The duration of study was I year.
Bilateral ECT combined with flupenthixol (18-24 mg/day) was used throughout. Brief Psychiatric
Rating Scale (BPRS), Global Assessment of Functioning (GAF), and Mini-Mental-State Exam
(MMSE) were used to measure the outcome. No patients suffered relapses. There were marked
reductions in BPRS scores (73 per cent and 70 per cent), and increases in GAF scores (68 per
cent and 91 per cent), at the end of Phases
I
and II, respectively. This study suggests a long-tem1
efficacy of ECT combined with neuroleptic therapy in patients with schizophrenia.
Key word : Electroconvulsive Therapy (ECT), Maintenance ECT, Treatment-Resistant
Schizophrenia, Prospective Study
inception in 1938, its efficacy as long-term treatment is still controversial. A 2-Phase, prospective
study has been conducted in 21 patients with schizophrenia. The duration of study was I year.
Bilateral ECT combined with flupenthixol (18-24 mg/day) was used throughout. Brief Psychiatric
Rating Scale (BPRS), Global Assessment of Functioning (GAF), and Mini-Mental-State Exam
(MMSE) were used to measure the outcome. No patients suffered relapses. There were marked
reductions in BPRS scores (73 per cent and 70 per cent), and increases in GAF scores (68 per
cent and 91 per cent), at the end of Phases
I
and II, respectively. This study suggests a long-tem1
efficacy of ECT combined with neuroleptic therapy in patients with schizophrenia.
Key word : Electroconvulsive Therapy (ECT), Maintenance ECT, Treatment-Resistant
Schizophrenia, Prospective Study
Download:
PDF