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Case ReportOpen Access
Typhoid Spondylodiscitis: the First Reported Case in Southeast Asia and Review of the Literature
Suwanpimolkul G 
,
Nilgate S ,
Suankratay C
,
Nilgate S ,
Suankratay C We describe the first case of typhoid spondylodiscitis in Southeast Asia, and the literature were also
reviewed. A 57-year-old diabetic Thai man who presented with a one-month course of progressive low back
pain associated with paraparesis and bowel-bladder dysfunction. Examination revealed local tenderness
over T12 area, spastic paraparesis, impaired pinprick sensation up to T12 level, and loose anal sphincter
tone. Magnetic resonance imaging showed spondylodiscitis of T11 and T12 and epidural abscess causing
spinal cord compression. T11 and T12 laminectomy, T11/12 discectomy, and debridement of epidural abscess
were performed, and the cultures of the pus grew Salmonella Typhi. He was treated with intravenous ciprofloxacin
for three weeks and was discharged from the hospital with oral ciprofloxacin and trimethoprimsulfamethoxazole
for another five months of treatment. The patient was doing well when last seen two months
after discontinuation of antimicrobial treatment. In addition, a total of ten cases of typhoid spondylitis/
spondylodiscitis were reviewed.
Keywords: Salmonella, Salmonella Typhi, Typhoid, Spondylodiscitis, Spondylitis, Epidural abscess
reviewed. A 57-year-old diabetic Thai man who presented with a one-month course of progressive low back
pain associated with paraparesis and bowel-bladder dysfunction. Examination revealed local tenderness
over T12 area, spastic paraparesis, impaired pinprick sensation up to T12 level, and loose anal sphincter
tone. Magnetic resonance imaging showed spondylodiscitis of T11 and T12 and epidural abscess causing
spinal cord compression. T11 and T12 laminectomy, T11/12 discectomy, and debridement of epidural abscess
were performed, and the cultures of the pus grew Salmonella Typhi. He was treated with intravenous ciprofloxacin
for three weeks and was discharged from the hospital with oral ciprofloxacin and trimethoprimsulfamethoxazole
for another five months of treatment. The patient was doing well when last seen two months
after discontinuation of antimicrobial treatment. In addition, a total of ten cases of typhoid spondylitis/
spondylodiscitis were reviewed.
Keywords: Salmonella, Salmonella Typhi, Typhoid, Spondylodiscitis, Spondylitis, Epidural abscess
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