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Original ArticleOpen Access
Methylcobalamin as an Adjuvant Medication in Conservative Treatment of Lumbar Spinal Stenosis
Waikakul W 
,
Waikakul S
,
Waikakul S To find out the clinical effects of methylcobalamin on the conservative treatment of
degenerative lumbar spinal stenosis, the study was carried out as a control single blind trial with 2
year follow-up in 152 patients, 68 males and 84 females, whose ages ranged from 55 to 85 years,
average 67
เธ‘
18.1 years. They were randomly allocated into 2 groups, the control group, 82
patients, and the methylcobalamin group, 70 patients. All had classical history, and physical
and radiographic findings which confirmed the diagnosis of spinal stenosis. Conventional
management, including patient education, physical therapy and medication, were carried out
in every patient and in addition methylcobalamin 0.5 mg was given orally three times a day in
the methylcobalamin group for 6 months. All patients were followed up periodically for 2 years.
Most of the patients in both groups showed improvement but there was no significant difference
between the 2 groups in terms of pain improvement and neurological signs, except neurogemc
claudication distance which was better in the M-group.
Key word : Spinal Stenosis, Vitamin B 12
degenerative lumbar spinal stenosis, the study was carried out as a control single blind trial with 2
year follow-up in 152 patients, 68 males and 84 females, whose ages ranged from 55 to 85 years,
average 67
เธ‘
18.1 years. They were randomly allocated into 2 groups, the control group, 82
patients, and the methylcobalamin group, 70 patients. All had classical history, and physical
and radiographic findings which confirmed the diagnosis of spinal stenosis. Conventional
management, including patient education, physical therapy and medication, were carried out
in every patient and in addition methylcobalamin 0.5 mg was given orally three times a day in
the methylcobalamin group for 6 months. All patients were followed up periodically for 2 years.
Most of the patients in both groups showed improvement but there was no significant difference
between the 2 groups in terms of pain improvement and neurological signs, except neurogemc
claudication distance which was better in the M-group.
Key word : Spinal Stenosis, Vitamin B 12
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