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Original ArticleOpen Access
Hepatocellular Carcinoma : Treated with Hepatic Arterial Embolization, an Analysis of Prognostic Features in 150 Cases
Eurvilaichit C 
,
Kanjanapitak A
,
Kanjanapitak A From July 1989 to July 1999, 120 male and 30 female patients with hepatocellular car-
cinoma (HCC), whose ages ranged from 18 to 71 years, were treated by different modalities. The
patients were divided into 3 groups according to treatment modalities : group I consisted of 35
cases treated by transarterial embolization (T AE) using gelatin sponge permeated with
mitomycin-c 20 mg, group 2 -100 cases treated by transcatheter oily chemoembolization (TOCE)
using lipiodol 10 cc with mitomycin-c 20 mg together with gelatin sponge for hepatic emboliza-
tion, and group 3-15 cases treated by TOCE followed by surgical wedge hepatic resection.
The prognostic features following treatments were retrospectively analysed in relation to
therapeutic modalities. The results revealed that TOCE was superior to TAE and that TOCE plus
adjunct wedge hepatic resection was the best treatment modality with the best cumulative sur-
gical rate (median survival 46.69 months).
Analysis of the life-table methods of group 2 patients revealed that the stage of tumors
and serum biochemistry on entry, both of which corresponded well with hepatic reserve function
were statistically significant prognostic factors for treatment result and long-term outcomes.
Further analysis of all the patients also revealed that tumor size and stage of tumors were sig-
nificant prognostic factors for the treatment of hepatocellular carcinomas.
Key word
: Hepatocellular Carcinoma, Embolization, Hepatic Resection
cinoma (HCC), whose ages ranged from 18 to 71 years, were treated by different modalities. The
patients were divided into 3 groups according to treatment modalities : group I consisted of 35
cases treated by transarterial embolization (T AE) using gelatin sponge permeated with
mitomycin-c 20 mg, group 2 -100 cases treated by transcatheter oily chemoembolization (TOCE)
using lipiodol 10 cc with mitomycin-c 20 mg together with gelatin sponge for hepatic emboliza-
tion, and group 3-15 cases treated by TOCE followed by surgical wedge hepatic resection.
The prognostic features following treatments were retrospectively analysed in relation to
therapeutic modalities. The results revealed that TOCE was superior to TAE and that TOCE plus
adjunct wedge hepatic resection was the best treatment modality with the best cumulative sur-
gical rate (median survival 46.69 months).
Analysis of the life-table methods of group 2 patients revealed that the stage of tumors
and serum biochemistry on entry, both of which corresponded well with hepatic reserve function
were statistically significant prognostic factors for treatment result and long-term outcomes.
Further analysis of all the patients also revealed that tumor size and stage of tumors were sig-
nificant prognostic factors for the treatment of hepatocellular carcinomas.
Key word
: Hepatocellular Carcinoma, Embolization, Hepatic Resection
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