J Med Assoc Thai 2000; 83 (3):141

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The Effect of Parity on Lipid Profile in Normal Pregnant Women
Sirikulchayanonta C Mail, Singsurapap W , Phuapradit W

A cross sectional study was carried out at Ramathibodi Hospital between June and August
1997. The objective of this study was to determine maternal serum lipid levels at delivery and
the effect of parity on maternal lipid profile. Study population was normal term pregnant women
aged 20-35 years who delivered normal infants with a birthweight ;:::, 2,500 grams. Maternal serum
lipid levels at delivery were determined from 177 normal term pregnant women. Their mean age
was 27.6เธ‘4.5 years. The first parity (Pl) was about 52 per cent, whereas, the second and third
parity (P2 and P3) were 37 and 11 per cent, respectively. Mean maternal serum total cholesterol
(TC) levels in Pl, P2 and P3 were 258.3เธ‘46.9, 266.7เธ‘47 .1 and 295.7เธ‘61.2 mg/dl, respec-
tively. Serum triglyceride (TG) levels in PI, P2 and P3 were 265.2เธ‘81.1, 280.3เธ‘72.1 and
260.7เธ‘82.8 mg/dl, respectively; serum low density lipoprotein-cholesterol (LDL-C) in PI, P2
and P3 were 136.9เธ‘45.2, 144.9เธ‘43.3 and 173.4เธ‘62.1 mg/dl, respectively; and serum high
density lipoprotein-cholesterol (HDL-C) levels were 64.6เธ‘16.6, 65.7เธ‘17.8, 67.2เธ‘16.0 mg/dl,
respectively. Serum TC and LDL-C levels increased with parity. There was a significant
difference between maternal TC and parity (F=4. 702, p=O.O 1) as well as LDL-C and parity
(F=4.883, p0.05).
Key word : Pregnant Women, Parity, Lipid Profile

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