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Case ReportOpen Access
Granular Cell Tumor of the Common Bile Duct : A Case Report
Granular cell tumors (GCTs) are uncommon soft tissue tumors, usually presenting in
the skin and subcutaneous tissue tongue and oral cavity. We present a case report of granular cell
tumor of the common bile duct involving both extra-and intrapancreatic portions. The histo-
genesis appears to be related to Schwann cells, similar to granular cell tumors of other sites, as
evidenced by histologic and immunohistochemical findings. Review of the English literature
concerning biliary tract GCTs revealed a high occurrence in African-American females in
their third decade. By-pass operation to correct the biliary tract obstruction may be appropriate.
if the nature of the tumor can be obtained from intraoperative diagnosis by frozen section.
Key word : Granular Cell Tumor, Common Bile Duct
the skin and subcutaneous tissue tongue and oral cavity. We present a case report of granular cell
tumor of the common bile duct involving both extra-and intrapancreatic portions. The histo-
genesis appears to be related to Schwann cells, similar to granular cell tumors of other sites, as
evidenced by histologic and immunohistochemical findings. Review of the English literature
concerning biliary tract GCTs revealed a high occurrence in African-American females in
their third decade. By-pass operation to correct the biliary tract obstruction may be appropriate.
if the nature of the tumor can be obtained from intraoperative diagnosis by frozen section.
Key word : Granular Cell Tumor, Common Bile Duct
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