J Med Assoc Thai 2001; 84 (1):12

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The Long Term Outcome of Thirty Eight Post-Transfusion Hepatitis C
Punyagupta S Mail, Siwadune T

Thirty-eight cases of post-transfustion HCV hepatitis have been followed for 5-24
years. Cirrhosis and hepatocellular carcinoma were found in 44.7 per cent and 13.1 per cent
respectively. Cirrhosis was recognised by pathological evidence as early as one and a half years
after transfusion and the clinical evidences of decompensated cirrhosis were noted in the fifth
year post-transfusion onward. Hepatocellular carcinoma was first recognised in year ten and
thereafter. Nine patients died of liver failure or hepatocellular carcinoma during years 8-16 of
the follow-up. Therefore, it is of utmost importance to screen out the HCV infected blood
donors and to treat the HCV patients as early and as effectively as possible.
Key word : Post-transfusion Hepatitis C, Cirrhosis, Hepatoma

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