Views: 1,263 | Downloads:
23
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Invasive Group A Streptococcal Infections at Chulalongkorn University Hospital
Suankratay C 
,
Nunthapisud P ,
Wilde H
,
Nunthapisud P ,
Wilde H CHUSANA SUANKRATAY, M.D., Ph.D.*,
PONG PUN NUNTHAPISUD,
M.Sc.
**,
HENRY WILDE, M.D.***
To determine whether the incidence and pattern of group A Streptococcal (GAS) infec-
tions in Thailand have paralleled those in the United States and Europe, we conducted a retro-
spective study of invasive GAS infections at Chulalongkom University Hospital from 1995 to
1999. A total of 42 cases were identified. There were 18 males and 24 females (median age of
59 and 46 years, respectively). Most patients were in two age groups: 20-39 (33%) and 60-79
(38% ). Underlying conditions were present in 34 patients (81% ), including mostly chronic system
diseases (50%), alcohol abuse (19%), diabetes mellitus (14%), connective tissue diseases (12%),
immunosuppressive illnesses (12%), and human immunodeficiency virus infection (10%). The most
common clinical presentations were skin and soft-tissue infections (31% ), primary bacteremia
(29%), and arthritis (14%). Of these, 24 (57%) presented with toxic shock syndrome (TSS). Overall
mortality rate was 33 per cent. All GAS but one isolate were susceptible to penicillin.
Key word
: Group A Streptococcal Infection, Toxic Shock Syndrome, Bacteremia
PONG PUN NUNTHAPISUD,
M.Sc.
**,
HENRY WILDE, M.D.***
To determine whether the incidence and pattern of group A Streptococcal (GAS) infec-
tions in Thailand have paralleled those in the United States and Europe, we conducted a retro-
spective study of invasive GAS infections at Chulalongkom University Hospital from 1995 to
1999. A total of 42 cases were identified. There were 18 males and 24 females (median age of
59 and 46 years, respectively). Most patients were in two age groups: 20-39 (33%) and 60-79
(38% ). Underlying conditions were present in 34 patients (81% ), including mostly chronic system
diseases (50%), alcohol abuse (19%), diabetes mellitus (14%), connective tissue diseases (12%),
immunosuppressive illnesses (12%), and human immunodeficiency virus infection (10%). The most
common clinical presentations were skin and soft-tissue infections (31% ), primary bacteremia
(29%), and arthritis (14%). Of these, 24 (57%) presented with toxic shock syndrome (TSS). Overall
mortality rate was 33 per cent. All GAS but one isolate were susceptible to penicillin.
Key word
: Group A Streptococcal Infection, Toxic Shock Syndrome, Bacteremia
Download:
PDF