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Case ReportOpen Access
Presumably Entomophtboramycosis in an HIV-Infected Patient: The First in Thailand
The authors reported the case of a symptomatic HIV-infected woman with a slowly progres-
sive infiltrative lesion which invaded in and around the nasal cavity over a 6-month period. Physi-
cal examination showed erythematous to violaceous plaques at the nasal and malar areas. Swelling
of the inferior turbinate was noted in the right nare. Skin biopsy of the involved area revealed
multiple nonseptate, broad, thin-walled hyphae within giant cells and granulomata. Entomophthora-
mycosis was diagnosed based on clinical features and histopathology. She was treated with intra-
venous amphotericin B for two weeks, followed by oral itraconazole 400 mg daily. At six months
there was complete resolution of all lesions.
Key word
: Entomophthoramycosis,
Conidiobolus,
Entomophthorales, HIV
sive infiltrative lesion which invaded in and around the nasal cavity over a 6-month period. Physi-
cal examination showed erythematous to violaceous plaques at the nasal and malar areas. Swelling
of the inferior turbinate was noted in the right nare. Skin biopsy of the involved area revealed
multiple nonseptate, broad, thin-walled hyphae within giant cells and granulomata. Entomophthora-
mycosis was diagnosed based on clinical features and histopathology. She was treated with intra-
venous amphotericin B for two weeks, followed by oral itraconazole 400 mg daily. At six months
there was complete resolution of all lesions.
Key word
: Entomophthoramycosis,
Conidiobolus,
Entomophthorales, HIV
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