J Med Assoc Thai 2001; 84 (12):1763

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Bupropion for Amphetamine Withdrawal Syndrome
ChanOb T Mail, Kuntawongse N , Boonyanaruthee V

This study was a case report of an amphetamine abuser who came to see doctor because
of amphetamine withdrawal syndrome three days after stopping prolonged use of amphetamine.
The patient was treated him with a slow-release bupropion at the dose of 150 mg per day.
After taking bupropion,
hi~
withdrawal symptoms i.e. dysphoric mood, fatigue, somnolence, and
psychomotor retardation gradually disappeared within two to three days. Moreover, his craving for
amphetamines was absent. The authors discussed the possible application for the clinical use for
amphetamine abusers or dependence.
Key word : Bupropion, Amphetamine Withdrawal, Amphetamine, Withdrawal Syndrome

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