J Med Assoc Thai 2001; 84 (4):584

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Peripheral Primitive Neuroectodermal Tumor with Neuronal and Glial Differentiation : Report of a Case Arising in Suprarenal Region
Chantranuwat C Mail

It is well known that embryonal neuroectodermal tumors of the central nervous system
(CNS) not infrequently display varying amount of neoplastic cells acquiring glial differentiation.
In contrast, glial differentiation rarely occurs in primitive neuroectodermal tumors outside the
CNS being documented in less than ten cases. The author presents herein a case of peripheral
primitive neuroectodermal tumor with prominent glial differentiation identified by the presence
of glial fibrillary acidic protein (GFAP) arising in the right suprarenal region of a 32-year-old
man, histologically indistinguishable from an ordinary neuroblastoma.
Key word : Primitive Neuroectodermal Tumor, Neuroglial Differentiation, Suprarenal Region

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