J Med Assoc Thai 2001; 84 (6):804

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Topical Ketorolac Tromethamine in the Reduction of Adverse Effects of Laser in Situ Keratomileusis
Kosrirukvongs P Mail, Srivannaboon S , Prabhasawat P , Pornpanich K

SABONG SRIV ANNABOON, M.D.*,
KANOGRAT PORNPANICH, M.D.*
Purpose : To evaluate whether topical ketorolac tromethamine can reduce the adverse
effect of laser in situ keratomileusis (LASIK).
Design : A prospective randomized controlled clinical study.
Participants : Nineteen patients who underwent bilateral simultaneous LASIK performed
at Siriraj Hospital.
Intervention : Patients received two drops of ketorolac tromethamine in one eye imme-
diately after surgery.
Main Outcome Measures : Symptoms of tearing, photophobia, foreign body sensation
and pain were evaluated at 30 minutes, 6 hours and 24 hours.
Results : There was no statistically significant difference in symptoms at 30 minutes. At
6 and 24 hours, ketorolac-treated eyes had significantly fewer symptoms compared to non-treated
eyes.
Conclusions : Ketorolac tromethamine reduces some unfavorable symptoms within the
first 24 hours after LASIK.
Key word : Laser
in Situ
Keratomileusis, Topical Ketorolac Tromethamine

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