J Med Assoc Thai 2001; 84 (6):837

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Effects of Clear Topical Ointment on Transepidermal Water Loss in Jaundiced Pretrem Infants Receiving Phototherapy
Wananukul S Mail, Praisuwanna P , Kesorncam K

Thirty jaundiced preterm infants, gestational age
5
34 weeks and postnatal age
5
7 days,
receiving conventional phototherapy for hyperbilirubinemia of prematurity in incubators were in-
cluded. 1.5 ml of clear topical ointment was applied on the right side of the trunk and extre-
mities while the left side was used as control. Data collection included transepidermal water loss
(TEWL), ambient temperature and ambient humidity, before and at 30 minutes, 4-6 hours after
application of the ointment during phototherapy. The measurements were executed both the right
and left side in 3 positions; upper arm, back, lower leg. TEWL was reduced by 29 per cent (P
value
<
0.002) and 26 per cent (P value
<
0.011) at 30 minutes and 4-6 hours after the applica-
tion of clear topical ointment, respectively. Ambient temperature and humidity were not signifi-
cantly different (P value
>
0.18). We concluded that application of clear topical ointment on the
skin of jaundiced preterm infants receiving conventional phototherapy in incubators reduced TEWL
significantly.
Key word : Transepidermal Water Loss, Phototherapy, Preterm Infant, Clear Topical Ointment

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