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Case ReportOpen Access
Risk Factors of Urethral involvement of Bladder Cancer After Radical Cystectomy with Orthotopic Neobladder in Females
Kochakam W 
,
Leenanupunth C ,
Chaimuangraj S ,
Muangman V
,
Leenanupunth C ,
Chaimuangraj S ,
Muangman V The cystectomy and urethrectomy specimens of 20 females with invasive bladder cancer
were studied for evidence of urethral involvement. The bladder showed transitional cell carcinoma
in 18 cases (90%) and squamous cell carcinoma in 2 cases ( 10% ). Urethral involvement was
found in 5 cases (25%). The trigone was the most common site of tumor (50%) which had 33 per
cent chance of urethral involvement. Bladder neck was the next common site of tumor (15%) and
had 66 per cent chance of urethral involvement. High stage (T3b, T4) and high grade (III) at
trigone also correlated with urethral involvement. The tumor bearing node showed only 20 per cent
correlation with urethral involvement. Female patients with high stage
I
high grade at trigone and
any stage
I
grade at bladder neck are at high risk of urethral recurrence after radical cystectomy
and orthotopic neobladder procedure.
Key word
: Bladder Cancer, Urethra, Cystectomy
were studied for evidence of urethral involvement. The bladder showed transitional cell carcinoma
in 18 cases (90%) and squamous cell carcinoma in 2 cases ( 10% ). Urethral involvement was
found in 5 cases (25%). The trigone was the most common site of tumor (50%) which had 33 per
cent chance of urethral involvement. Bladder neck was the next common site of tumor (15%) and
had 66 per cent chance of urethral involvement. High stage (T3b, T4) and high grade (III) at
trigone also correlated with urethral involvement. The tumor bearing node showed only 20 per cent
correlation with urethral involvement. Female patients with high stage
I
high grade at trigone and
any stage
I
grade at bladder neck are at high risk of urethral recurrence after radical cystectomy
and orthotopic neobladder procedure.
Key word
: Bladder Cancer, Urethra, Cystectomy
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