J Med Assoc Thai 2001; 84 (7):1033

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Detection of Endometrial Cancer in Asymptomatic Postmenopausal Breast Cancer Patient Treated with Tamoxifen : A Case Report
Sinawat S Mail, Chiyabutra T , Kleabkaew P

Breast cancer is among the commonest malignancies in women and tamoxifen has been
widely used for more than two decades for treatment of breast cancer. It has been known that long
term use of tamoxifen significantly increases the risk of endometrial cancer but there is no generally
accepted recommendation regarding the surveillance of endometrial pathologies in breast cancer
patients taking tamoxifen. Although the incidence of endometrial cancer associated with tamoxifen
use is not high, the risk is true and these patients could be helped by screening methods such as
transvaginal ultrasonogrphy. We report here a case of endometrial cancer detected by transvaginal
2D scan in an asymptomatic postmenopausal woman taking tamoxifen.
Key word : Tamoxifen, Endometrial Cancer

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