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Original ArticleOpen Access
Advanced Epithelial Ovarian Carcinoma in Thai Women: Should We Continue to Offer Second-Look Laparotomy?
Linasmita V 
,
Wilailak S ,
Thakkinstian A ,
Srisupundit S ,
Tangtrakul S ,
lsrangura N ,
Bullangpoti S
,
Wilailak S ,
Thakkinstian A ,
Srisupundit S ,
Tangtrakul S ,
lsrangura N ,
Bullangpoti S SARIKAPAN WILAILAK, M.D.*,
SOMKEART SRISUPUNDIT, M.D.*,
NATHPONG ISRANGURA, M.D.*,
Objective
: To determine survival among patients with epithelial ovarian carcinoma (EOC)
who underwent a second-look laparotomy (SLL) and those refusing the procedure. Also to analyze
factor(s) influencing the survival of the patients.
Method and Material
: Medical records were reviewed of patients with advanced EOC
who were clinically free of disease after primary surgery and platinum-based chemotherapy between
January I, 1992, and December 31, 1998. All of them were offered SLL. Measurement outcomes
include patient survival and disease-free survival.
Results
: There were 50 patients with clinically complete remission after chemotherapy.
Sixteen patients underwent SLL, and thirty-four patients refused the procedure (NSLL). Seven
patients (43.8%) were reported to have positive SLL. After the median follow-up time of 35
months, 12 patients had died, and 5 patients were lost to follow-up. The median survival time for
patients with SLL was about 60 months. Five-year survival rates of patients in the SLL, and NSLL
groups were 37 per cent (95%CI = 7%-69%), and 88 per cent (95%CI = 65%-96%) respectively
(P
SOMKEART SRISUPUNDIT, M.D.*,
NATHPONG ISRANGURA, M.D.*,
Objective
: To determine survival among patients with epithelial ovarian carcinoma (EOC)
who underwent a second-look laparotomy (SLL) and those refusing the procedure. Also to analyze
factor(s) influencing the survival of the patients.
Method and Material
: Medical records were reviewed of patients with advanced EOC
who were clinically free of disease after primary surgery and platinum-based chemotherapy between
January I, 1992, and December 31, 1998. All of them were offered SLL. Measurement outcomes
include patient survival and disease-free survival.
Results
: There were 50 patients with clinically complete remission after chemotherapy.
Sixteen patients underwent SLL, and thirty-four patients refused the procedure (NSLL). Seven
patients (43.8%) were reported to have positive SLL. After the median follow-up time of 35
months, 12 patients had died, and 5 patients were lost to follow-up. The median survival time for
patients with SLL was about 60 months. Five-year survival rates of patients in the SLL, and NSLL
groups were 37 per cent (95%CI = 7%-69%), and 88 per cent (95%CI = 65%-96%) respectively
(P
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