Views: 1,264 | Downloads:
22
| Responses: 0
| XML | Respond to this article | Alert & updates | Request permissions | Email to a friend |
Original ArticleOpen Access
Serum Magnesium in Thai Coronary Artery Disease Patients
Wannasilp N 
,
Leowattana W ,
Poungvarin N ,
Mahanonda N ,
Pokum S
,
Leowattana W ,
Poungvarin N ,
Mahanonda N ,
Pokum S WATT ANA LEOWATTANA, M.D.*,
NITHI MAHANONDA, M.D.**,
Hypomagnesemia or magnesium (Mg) deficiency has been hypothesized to play a role
in coronary artery disease (CAD). The authors aimed to evaluate serum Mg concentration in 100
CAD patients compared with 100 healthy controls. Mean values of serum Mg level in CAD and
the control group were 2.14
เธ‘
0.39, 2.24
เธ‘
0.3 mg/dL respectively (P=0.052). The prevalence of
Mg deficiency was 12 per cent in the CAD patients, and 5 per cent in the control group (odds
ratio=2.59, 95% confident interval=0.88-7.65, P=0.063). There was no significant difference in
the serum Mg level between the 2 groups, although it tended to be lower in CAD patients. The
prevalence of Mg deficiency did not differ significantly between the study group, however, it
tended to be higher in CAD patients. These findings demonstrated that CAD patients may be asso-
ciated with Mg deficiency, and contribute to the pathogenesis of CAD or acute thrombosis. Fol-
lowing this evidence, Mg treatment may be necessary in CAD patients with Mg deficiency or
acute myocardial infarction (AMI).
Key word
: Magnesium, Magnesium Deficiency, Coronary Artery Disease
NITHI MAHANONDA, M.D.**,
Hypomagnesemia or magnesium (Mg) deficiency has been hypothesized to play a role
in coronary artery disease (CAD). The authors aimed to evaluate serum Mg concentration in 100
CAD patients compared with 100 healthy controls. Mean values of serum Mg level in CAD and
the control group were 2.14
เธ‘
0.39, 2.24
เธ‘
0.3 mg/dL respectively (P=0.052). The prevalence of
Mg deficiency was 12 per cent in the CAD patients, and 5 per cent in the control group (odds
ratio=2.59, 95% confident interval=0.88-7.65, P=0.063). There was no significant difference in
the serum Mg level between the 2 groups, although it tended to be lower in CAD patients. The
prevalence of Mg deficiency did not differ significantly between the study group, however, it
tended to be higher in CAD patients. These findings demonstrated that CAD patients may be asso-
ciated with Mg deficiency, and contribute to the pathogenesis of CAD or acute thrombosis. Fol-
lowing this evidence, Mg treatment may be necessary in CAD patients with Mg deficiency or
acute myocardial infarction (AMI).
Key word
: Magnesium, Magnesium Deficiency, Coronary Artery Disease
Download:
PDF