J Med Assoc Thai 2002; 85 (1):102

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Clear Topical Ointment Decreases Transepidermal Water Loss in Jaundiced Preterm Infants Receiving Phototherapy
Wananukul S Mail, Praisuwanna P

SIRIWAN WANANUKUL,M.D.*,
PRAMOTE PRAISUW ANNA, M.D.**
The evaporation rate (ER) from the skin was measured in 40 jaundiced preterm infants born
at less than or equal to 34 weeks of gestation. The baseline measurements were executed in both
the right and left side in 3 positions: upper arm, back and lower leg. The patients were randomly
recruited to a treatment or a control group. The treatment group received 3.0 ml of clear topical
ointment just before phototherap,y. Conventional phototherapy was placed above the incubators in
both groups. ER and ambient skin temperature were measured at the same point at 30 minutes and
5
hours during phototherapy.
In the control group, ER was increased by 8.0 per cent (P value= 0.01) and 14.5 per cent (P
value< 0.001) at 30 minutes and
5
hours during phototherapy, respectively. In the treatment group,
clear topical ointment decreased ER by 19.2 per cent (P value< 0.001) and 13.2 per cent (P value=
0.003) at 30 minutes and
5
hours during phototherapy, respectively. Ambient skin temperature
during phototherapy was increased significantly (P

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