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Case ReportOpen Access
Severe Upper Gastrointestinal Hemorrhage in the Newborn
Three infants with severe upper gastrointestinal hemorrhage with esophagogastroduodeno-
scopic (EGD) findings were reported. The underlying conditions of these infants included Down's
syndrome, hypoplastic left heart, arid diaphragmatic hernia. The precipitating factors were identified
in all cases, including prenatal stress, hypoxemia, prolonged ventilatory support, and gastroesopha-
geal reflux. The EGD findings were composed of multiple gastric ulcers and a duodenal ulcer in
the first 2 cases, whereas esophagitis and gastritis were noted in the last case. These ulcers were
classified as secondary peptic ulcers. All cases responded well to medical treatment, including
ranitidine, sucralfate, omeprazole, cisapridt;.._. and octreotide.
Key word
: Gastrointestinal Hemorrhage, Newborn, Esophagogastroduodenoscopy
scopic (EGD) findings were reported. The underlying conditions of these infants included Down's
syndrome, hypoplastic left heart, arid diaphragmatic hernia. The precipitating factors were identified
in all cases, including prenatal stress, hypoxemia, prolonged ventilatory support, and gastroesopha-
geal reflux. The EGD findings were composed of multiple gastric ulcers and a duodenal ulcer in
the first 2 cases, whereas esophagitis and gastritis were noted in the last case. These ulcers were
classified as secondary peptic ulcers. All cases responded well to medical treatment, including
ranitidine, sucralfate, omeprazole, cisapridt;.._. and octreotide.
Key word
: Gastrointestinal Hemorrhage, Newborn, Esophagogastroduodenoscopy
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