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Original ArticleOpen Access
Epidemiological Correlation Between Chromium Content in Gallstones and Cholesterol in Blood
Shigeta A 
,
Moriyama Y ,
Ratanamaneechat S ,
Suwanagool S ,
Srisukho S ,
Miki M ,
Tanaka M
,
Moriyama Y ,
Ratanamaneechat S ,
Suwanagool S ,
Srisukho S ,
Miki M ,
Tanaka M YUKICHI MORIYAMA, M.D.*,
SURAPOL SUWANAGOOL, M.D.**,
MASARU MIKI, M.D.****,
The authors measured the chromium in gallstones and bile from patients in three areas
(Kawasaki (a city adjacent to Tokyo) in Japan, Chiang Mai and Bangkok in Thailand) by means
of neutron activation analysis. The chromium in three types of gallstones (cholesterol, pigment,
and rare stones) and bile from patients living in Bangkok were evidently larger than those from
patients living in Kawasaki and Chiang Mai. The high chromium intake by Bangkok patients
continued from the start of gallstone formation until the time the stones were removed. The total-
cholesterol, triglyceride, and hemoglobin A
1
c levels in the blood from Bangkok residents with high
chromium intake over a long period were clearly lower than those of Japanese and Chiang Mai
residents. The authors showed that the high dietary intake of chromium over a long period may
play a role in the lowering of total-cholesterol, triglyceride, and hemoglobin A
1
c in blood.
Key word
: Chromium Levels, Gallstones, Bile, Japanese, Thais, Total-Cholesterol, Triglyceride,
Hemoglobin A
1
c
SURAPOL SUWANAGOOL, M.D.**,
MASARU MIKI, M.D.****,
The authors measured the chromium in gallstones and bile from patients in three areas
(Kawasaki (a city adjacent to Tokyo) in Japan, Chiang Mai and Bangkok in Thailand) by means
of neutron activation analysis. The chromium in three types of gallstones (cholesterol, pigment,
and rare stones) and bile from patients living in Bangkok were evidently larger than those from
patients living in Kawasaki and Chiang Mai. The high chromium intake by Bangkok patients
continued from the start of gallstone formation until the time the stones were removed. The total-
cholesterol, triglyceride, and hemoglobin A
1
c levels in the blood from Bangkok residents with high
chromium intake over a long period were clearly lower than those of Japanese and Chiang Mai
residents. The authors showed that the high dietary intake of chromium over a long period may
play a role in the lowering of total-cholesterol, triglyceride, and hemoglobin A
1
c in blood.
Key word
: Chromium Levels, Gallstones, Bile, Japanese, Thais, Total-Cholesterol, Triglyceride,
Hemoglobin A
1
c
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