J Med Assoc Thai 2002; 85 (6):728

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Upward Gaze Paralysis as the Initial Manifestation of HIV-Infected Patient : A Case Report
Kitthaweesin K Mail

Upward gaze palsy developed in a 23-year-old man without any other abnormal findings
except pupillary light-near dissociation in ocular examination. The neuroradiologic examination was
consistent with cerebral toxoplasmosis -the most frequent opportunistic infection of the brain in
AIDS patients. The serologic work-up revealed a positive HIV test. Symptoms and neuroradiologic
abnormality improved after treatment for cerebral toxoplasmosis. HIV infection should be considered
in patients who have upward gaze paralysis and neuroimaging compatible with cerebral toxoplasmosis.
Empirical treatment may alleviate the upward gaze palsy.
Key word : Upward Gaze Paralysis, Initial Manifestation, HIV, AIDS

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