J Med Assoc Thai 2002; 85 (8):901

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Prevalence of Thyroid Antibodies in Thai Patients with Chronic Idiopathic Urticaria
Kullavanijaya P Mail, Puavilai S , Puavilai G , Chanprasertyothin S

One hundred Thai patients with chronic idiopathic urticaria (CIU) were studied to determine
the prevalence of thyroid antibodies in comparison to 100 age-and sex-matched healthy volunteers.
It
was found that 21 patients (21%) with CIU were positive for thyroid antibodies. Among normal
volunteers, only nine cases (9%) had elevated titers of thyroid antibodies. The frequency of thyroid
antibodies in the chronic urticaria group was significantly more common than the control group
(chi-square= 4.75, p=0.03). Among 21 patients with CIU who were positive for thyroid antibodies,
9 cases were negative for thyroid antibodies when repeating the tests after 3 months. Only 12
patients still had persistent elevation of antibodies after 3 months and thyroid function test was per-
formed in these 12 patients. It was found that 9 cases had autoimmune thyroiditis with euthyroidism.
One case had subclinical hyperthyroidism. One case had autoimmune hyperthyroidism. One case had
subclinical hypothyroidism.
Key word : Hives, Autoimmune Thyroiditis, Hypothyroidism, Hyperthyroidism

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