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Original ArticleOpen Access
Influence of Normal Ageing on Mechanism of Bone Loss in Women and Men in Bangkok
Chailurkit L 
,
Piaseu N ,
Rajatanavin R
,
Piaseu N ,
Rajatanavin R Age and sex related changes in bone metabolism are of interest in the pathogenesis of
osteoporosis. However, most data in the literature were studied in Western countries. In a tropical
country, such as Thailand, little is known of vitamin D status and bone remodeling. Thus, the aim
of this study was to determine the changes of vitamin D levels and biochemical markers of bone
turnover in healthy women and men of various age groups between 20-80 years who were living in
Bangkok. From the results, vitamin D levels of various age groups did not alter significantly between
men and women except in the sixth decade of women. However, men had higher levels of vitamin
D than women. In women, all biochemical markers of bone turnover increased with age, with a
sharp increase at the onset of menopause. In contrast, biochemical markers of bone turnover in men
gradually declined with advancing age.
Conclusion
:
There was no evidence of vitamin D deficiency in the Bangkok population.
Women and men showed different age-related changes in bone metabolism.
Key word
:
Vitamin D, Bone Markers, Bone Loss
osteoporosis. However, most data in the literature were studied in Western countries. In a tropical
country, such as Thailand, little is known of vitamin D status and bone remodeling. Thus, the aim
of this study was to determine the changes of vitamin D levels and biochemical markers of bone
turnover in healthy women and men of various age groups between 20-80 years who were living in
Bangkok. From the results, vitamin D levels of various age groups did not alter significantly between
men and women except in the sixth decade of women. However, men had higher levels of vitamin
D than women. In women, all biochemical markers of bone turnover increased with age, with a
sharp increase at the onset of menopause. In contrast, biochemical markers of bone turnover in men
gradually declined with advancing age.
Conclusion
:
There was no evidence of vitamin D deficiency in the Bangkok population.
Women and men showed different age-related changes in bone metabolism.
Key word
:
Vitamin D, Bone Markers, Bone Loss
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