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Case ReportOpen Access
Acquired Reactive Perforating Collagenosis : Report of a Case and Review of the Literature
A case of acquired reactive perforating collagenosis is reported in a 57-year-old Thai woman,
with a history of diabetes mellitus, chronic renal insufficiency needing hemodialysis, and dry gangrene
of the right fourth toe. Physical examination revealed multiple scattered erythematous hyperkeratotic
nodules and plaques and some showed ulceration. Histopathology showed vertical strands of collagen
perforating from the ulcerated lesions. The authors also reviewed the literature on this subject.
Key word : Reactive Perforating Collagenosis, Diabetes Mellitus, Chronic Renal Insufficiency
with a history of diabetes mellitus, chronic renal insufficiency needing hemodialysis, and dry gangrene
of the right fourth toe. Physical examination revealed multiple scattered erythematous hyperkeratotic
nodules and plaques and some showed ulceration. Histopathology showed vertical strands of collagen
perforating from the ulcerated lesions. The authors also reviewed the literature on this subject.
Key word : Reactive Perforating Collagenosis, Diabetes Mellitus, Chronic Renal Insufficiency
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