J Med Assoc Thai 2002; 85 (9):968

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The Efficacy and Tolerability of an Angiotensin II Receptor Blocker, Telmisartan, in Thai Patients with Mild to Moderate Essential Hypertension
Buranakitjaroen P Mail, Phoojaroenchanachai M , Saravich S , Sangprasert P

This open-labeled single-blinded study was performed to evaluate the efficacy and tolerability
of telmisartan in the treatment of mild to moderate essential hypertension. Each patient was assigned
to take a placebo for 4 weeks followed by once daily-titrated telmisartan (40-80 mg) for 8 weeks.
"Office BP" and "24-hour ambulatory BP" measurements (24-h ABPM) were recorded as scheduled.
Thirty-one patients (10 males : 21 females) with a mean age of 48.1 years were enrolled. The final
SBP/DBP reductions of 14.6
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14.2/9.9
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6.2 mm Hg were obtained. Full response defined as office
DBP reduction of 2!:10 mm Hg from baseline and/or DBP

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