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Original ArticleOpen Access
Serum Sickness and Hepatitis B Vaccine Including Review of the Literature
Arkachaisri T 
HB vaccine is one of the most widely administered vaccines in the world. Its efficacy
approaches 95 per cent. The majority of adverse reactions are generally mild, although there have
been individual case reports of serious reactions since the vaccine has become commercially avai-
lable. Here, a patient with a serum sickness-like reaction after her second HB immunization is
reported. Review of the literature for reports of serious adverse reactions to the vaccine was also
carried out.
Key word : Hepatitis B Vaccine, Serum Sickness, Adverse Reactions
approaches 95 per cent. The majority of adverse reactions are generally mild, although there have
been individual case reports of serious reactions since the vaccine has become commercially avai-
lable. Here, a patient with a serum sickness-like reaction after her second HB immunization is
reported. Review of the literature for reports of serious adverse reactions to the vaccine was also
carried out.
Key word : Hepatitis B Vaccine, Serum Sickness, Adverse Reactions
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