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Original ArticleOpen Access
High CD 4 + T -cells Percentage and/or Low Viral Load are Predictors of 1-5 Years Survival in HIV-1 Vertically Infected Thai Children
Vanprapar N 
,
Chearsakul S ,
Chokephaibulkit K ,
Phongsaman W ,
Lolekha Rs
,
Chearsakul S ,
Chokephaibulkit K ,
Phongsaman W ,
Lolekha Rs Objective : Enrolling pediatric HIV children into the clinical trial of when to initiate anti-
retroviral therapy is a crucial ethical issue. CD
4
+
T-cells percentage and /or viral load were able to
identify potential cases of survival through
5
years of age.
Method : HIV infected cohort from 1992 to 1994 from Children's and Siriraj Hospitals
were followed from 1 through
5
years of age. The outcome was survival or death. The predictors
were CD4 percentage and viral load (without age and clinical status adjustment).
Result : 16 of 35 ( 45.71%) of the cohort survived through
5
years of age. The probability
of survival increased to almost 100 per cent either with CD
4
+
T-cells percentage of over 22 or viral
load of less than 500,000.
Key word : CD
4
+
T-cells Percentage, Viral Load, HIV-Infected Children, Survival
retroviral therapy is a crucial ethical issue. CD
4
+
T-cells percentage and /or viral load were able to
identify potential cases of survival through
5
years of age.
Method : HIV infected cohort from 1992 to 1994 from Children's and Siriraj Hospitals
were followed from 1 through
5
years of age. The outcome was survival or death. The predictors
were CD4 percentage and viral load (without age and clinical status adjustment).
Result : 16 of 35 ( 45.71%) of the cohort survived through
5
years of age. The probability
of survival increased to almost 100 per cent either with CD
4
+
T-cells percentage of over 22 or viral
load of less than 500,000.
Key word : CD
4
+
T-cells Percentage, Viral Load, HIV-Infected Children, Survival
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